Multiparameter Flow cytometry shines a light on interactions between human spleen cells and extracellular vesicles from Plasmodium vivax patients
The Plasmodium vivax and Exosome Research Group (PVREX) has worked closely with the Cytometry Core Facility of the IGTP to use multiparameter cytometry combined with cell purification techniques to study the complex cell populations in the human spleen. The study published in Frontiers in Cellular and Infection Microbiology also looked at the interactions extracellular vesicles taken from plasma from patients with Plasmodium vivax infections, a parasite which causes malaria, and the different types of spleen cells. This is the first time this type of study has been done using spleen samples from donors.