Publications

Martinez-Velasco M, Sánchez-Herrero JF, Ibañez L, Velli P, Muñoz-Lopez FM, Cairó M, Jaen A, Font R, Martinez-Lacasa X, Royo J, Peraire J, Faro-Míguez N, Rivero A, Olalla J, Ruiz-Seco P, López-Cortés LF, Sumoy L, Massanella M, Dalmau D; HUMT and CoRIS Cohorts. Circulating miRNA Signatures Associated with Atherosclerosis and Cardiometabolic Comorbidities in People with HIV. Med Sci (Basel). 2026 Feb 12;14(1). DOI: 10.3390/medsci14010085.

Clua L, Suau R, Guasch M, Monfort-Ferré D, Boronat-Toscano A, Aquino M, Matute-Molina K, Jimeno M, Mañosa M, Sumoy L, Domènech E, Bartolí R, Manyé J, Serena C. Characterization of mesocolic adipose hyperplasia in a rat 2,4,6-trinitrobenzenesulfonic acid colitis model and comparison to creeping fat in Crohn disease. Inflamm Bowel Dis. 2026 Apr 1;32(4):610-619. DOI: 10.1093/ibd/izaf328.

Boronat-Toscano A, Queipo-Ortuño MI, Monfort-Ferré D, Suau R, Vañó-Segarra I, Valldosera G, Cepero C, Astiarraga B, Clua-Ferré L, Plaza-Andrade I, Aranega-Martín L, Cabrinety L, Abadia de Barbarà C, Castellano-Castillo D, Moliné A, Caro A, Domènech E, Sánchez-Herrero JF, Benaiges-Fernandez R, Fernández-Veledo S, Vendrell J, Ginés I, et al. Dialister-driven succinate accumulation is associated with disease activity and postoperative recurrence in Crohn's disease. World J Gastroenterol. 2025 Dec 7;31(45):112618. DOI: 10.3748/wjg.v31.i45.112618.

Santos-Pujol E, Noguera-Castells A, Casado-Pelaez M, García-Prieto CA, Vasallo C, Campillo-Marcos I, Quero-Dotor C, Crespo-García E, Bueno-Costa A, Setién F, Ferrer G, Davalos V, Mereu E, Pluvinet R, Arribas C, Torre C, Villavicencio F, Sumoy L, Granada I, Coles NS, Acha P, Solé F, et al. The multiomics blueprint of the individual with the most extreme lifespan. Cell Rep Med. 2025 Oct 21;6(10):102368. DOI: 10.1016/j.xcrm.2025.102368.

Reyes-Farias M, Fernández-García P, Corrales P, González L, Navarro-Sanagustín D, Soria-Gondek A, Pellitero S, Tarascó J, Moreno P, Balibrea JM, Gatell L, Sumoy L, Galán M, Martínez E, Villarroya F, Cereijo R, Herrero L, Sánchez-Infantes D. Lipid-associated macrophages are more abundant in subcutaneous than visceral adipose tissue in patients with obesity. Obesity (Silver Spring). 2025 Aug;33(8):1543-1554. DOI: 10.1002/oby.24323.

Rodríguez-Lloveras H, Zafon C, Iglesias C, Marcos-Ruiz J, Gil J, Rueda-Pujol A, González L, Mayor R, Klein Hesselink EN, van Hemel BM, Carrato C, Perelló-Fabregat C, Hernández-Losa J, Somoza R, Pluvinet R, Sánchez-Herrero JF, Sumoy L, Seoane J, Riesco-Eizaguirre G, Montero-Conde C, Robledo M, Hernando J, et al. DNA Methylation Dynamics and Prognostic Implications in Metastatic Differentiated Thyroid Cancer. Thyroid. 2025 May;35(5):494-507. DOI: 10.1089/thy.2024.0303.

Cárcel-Márquez J, Muiño E, Gallego-Fabrega C, Cullell N, Lledós M, Llucià-Carol L, Martín-Campos JM, Sobrino T, Campos F, Castillo J, Freijo M, Arenillas JF, Obach V, Álvarez-Sabín J, Molina CA, Ribó M, Jiménez-Conde J, Roquer J, Muñoz-Narbona L, Lopez-Cancio E, Millán M, Diaz-Navarro R, et al. Sex-Stratified Genome-Wide Association Study in the Spanish Population Identifies a Novel Locus for Lacunar Stroke. Stroke. 2024 Oct;55(10):2462-2471. DOI: 10.1161/STROKEAHA.124.047833.

Monfort-Ferré D, Boronat-Toscano A, Sánchez-Herrero JF, Caro A, Menacho M, Vañó-Segarra I, Martí M, Espina B, Pluvinet R, Cabrinety L, Abadia C, Ejarque M, Nuñez-Roa C, Maymo-Masip E, Sumoy L, Vendrell J, Fernández-Veledo S, Serena C. Genome-wide DNA Methylome and Transcriptome Profiling Reveals Key Genes Involved in the Dysregulation of Adipose Stem Cells in Crohn's Disease. J Crohns Colitis. 2024 Oct 15;18(10):1644-1659. DOI: 10.1093/ecco-jcc/jjae072.

Ferre-Giraldo A, Castells M, Sánchez-Herrero JF, López-Rodrigo O, de Rocco-Ponce M, Bassas L, Vigués F, Sumoy L, Larriba S. Semen sEV tRF-Based Models Increase Non-Invasive Prediction Accuracy of Clinically Significant Prostate Cancer among Patients with Moderately Altered PSA Levels. Int J Mol Sci. 2024 Sep 20;25(18). DOI: 10.3390/ijms251810122.

Reyes-Farias M, Fernández-García P, Corrales P, González L, Soria-Gondek A, Martínez E, Pellitero S, Tarascó J, Moreno P, Sumoy L, Medina-Gómez G, Sánchez-Infantes D, Herrero L. Interleukin-16 is increased in obesity and alters adipogenesis and inflammation in vitro. Front Endocrinol (Lausanne). 2024 Mar 13;15:1346317. DOI: 10.3389/fendo.2024.1346317.

Villalba A, Rodriguez-Fernandez S, Perna-Barrull D, Ampudia RM, Gomez-Muñoz L, Pujol-Autonell I, Aguilera E, Risueño RM, Cano-Sarabia M, Maspoch D, Vázquez F, Vives-Pi M. Antigen-specific immunotherapy combined with a regenerative drug in the treatment of experimental type 1 diabetes. Sci Rep. 2020 Nov 3;10(1):18927. DOI: 10.1038/s41598-020-76041-1.

Sanchez-Herrero JF, Bernabeu M, Prieto A, Hüttener M, Juárez A. Gene Duplications in the Genomes of Staphylococci and Enterococci. Front Mol Biosci. 2020 Jul 23;7:160. DOI: 10.3389/fmolb.2020.00160.

Dámaso E, González-Acosta M, Vargas-Parra G, Navarro M, Balmaña J, Ramon Y Cajal T, Tuset N, Thompson BA, Marín F, Fernández A, Gómez C, Velasco À, Solanes A, Iglesias S, Urgel G, López C, Del Valle J, Campos O, Santacana M, Matias-Guiu X, Lázaro C, Valle L, et al. Comprehensive Constitutional Genetic and Epigenetic Characterization of Lynch-Like Individuals. Cancers (Basel). 2020 Jul 5;12(7). DOI: 10.3390/cancers12071799.

Ilett EE, Jørgensen M, Noguera-Julian M, Daugaard G, Murray DD, Helleberg M, Paredes R, Lundgren J, Sengeløv H, MacPherson C. Gut microbiome comparability of fresh-frozen versus stabilized-frozen samples from hospitalized patients using 16S rRNA gene and shotgun metagenomic sequencing. Sci Rep. 2019 Sep 16;9(1):13351. DOI: 10.1038/s41598-019-49956-7.

Carrió M, Mazuelas H, Richaud-Patin Y, Gel B, Terribas E, Rosas I, Jimenez-Delgado S, Biayna J, Vendredy L, Blanco I, Castellanos E, Lázaro C, Raya Á, Serra E. Reprogramming Captures the Genetic and Tumorigenic Properties of Neurofibromatosis Type 1 Plexiform Neurofibromas. Stem Cell Reports. 2019 Mar 5;12(3):639-641. DOI: 10.1016/j.stemcr.2019.02.001.

Lozano-Ramos SI, Bancu I, Carreras-Planella L, Monguió-Tortajada M, Cañas L, Juega J, Bonet J, Armengol MP, Lauzurica R, Borràs FE. Molecular profile of urine extracellular vesicles from normo-functional kidneys reveal minimal differences between living and deceased donors. BMC Nephrol. 2018 Jul 31;19(1):189. DOI: 10.1186/s12882-018-0985-3.

Carrió M, Gel B, Terribas E, Zucchiatti AC, Moliné T, Rosas I, Teulé Á, Ramón Y Cajal S, López-Gutiérrez JC, Blanco I, Castellanos E, Lázaro C, Stemmer-Rachamimov A, Romagosa C, Serra E. Analysis of intratumor heterogeneity in Neurofibromatosis type 1 plexiform neurofibromas and neurofibromas with atypical features: Correlating histological and genomic findings. Hum Mutat. 2018 Aug;39(8):1112-1125. DOI: 10.1002/humu.23552.

Palomo L, Malinverni R, Cabezón M, Xicoy B, Arnan M, Coll R, Pomares H, García O, Fuster-Tormo F, Grau J, Feliu E, Solé F, Buschbeck M, Zamora L. DNA methylation profile in chronic myelomonocytic leukemia associates with distinct clinical, biological and genetic features. Epigenetics. 2018;13(1):8-18. DOI: 10.1080/15592294.2017.1405199.

Posavec Marjanović M, Hurtado-Bagès S, Lassi M, Valero V, Malinverni R, Delage H, Navarro M, Corujo D, Guberovic I, Douet J, Gama-Perez P, Garcia-Roves PM, Ahel I, Ladurner AG, Yanes O, Bouvet P, Suelves M, Teperino R, Pospisilik JA, Buschbeck M. MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD(+) consumption. Nat Struct Mol Biol. 2017 Nov;24(11):902-910. DOI: 10.1038/nsmb.3481.

Izquierdo-Bouldstridge A, Bustillos A, Bonet-Costa C, Aribau-Miralbés P, García-Gomis D, Dabad M, Esteve-Codina A, Pascual-Reguant L, Peiró S, Esteller M, Murtha M, Millán-Ariño L, Jordan A. Histone H1 depletion triggers an interferon response in cancer cells via activation of heterochromatic repeats. Nucleic Acids Res. 2017 Nov 16;45(20):11622-11642. DOI: 10.1093/nar/gkx746.

Jordà M, Díez-Villanueva A, Mallona I, Martín B, Lois S, Barrera V, Esteller M, Vavouri T, Peinado MA. The epigenetic landscape of Alu repeats delineates the structural and functional genomic architecture of colon cancer cells. Genome Res. 2017 Jan;27(1):118-132. DOI: 10.1101/gr.207522.116.

Buj R, Mallona I, Díez-Villanueva A, Barrera V, Mauricio D, Puig-Domingo M, Reverter JL, Matias-Guiu X, Azuara D, Ramírez JL, Alonso S, Rosell R, Capellà G, Perucho M, Robledo M, Peinado MA, Jordà M. Quantification of unmethylated Alu (QUAlu): a tool to assess global hypomethylation in routine clinical samples. Oncotarget. 2016 Mar 1;7(9):10536-46. DOI: 10.18632/oncotarget.7233.

Mayor R, Izquierdo-Bouldstridge A, Millán-Ariño L, Bustillos A, Sampaio C, Luque N, Jordan A. Genome distribution of replication-independent histone H1 variants shows H1.0 associated with nucleolar domains and H1X associated with RNA polymerase II-enriched regions. J Biol Chem. 2015 Mar 20;290(12):7474-91. DOI: 10.1074/jbc.M114.617324.

Alonso S, Dai Y, Yamashita K, Horiuchi S, Dai T, Matsunaga A, Sánchez-Muñoz R, Bilbao-Sieyro C, Díaz-Chico JC, Chernov AV, Strongin AY, Perucho M. Methylation of MGMT and ADAMTS14 in normal colon mucosa: biomarkers of a field defect for cancerization preferentially targeting elder African-Americans. Oncotarget. 2015 Feb 20;6(5):3420-31. DOI: 10.18632/oncotarget.2852.

Creppe C, Palau A, Malinverni R, Valero V, Buschbeck M. A Cbx8-containing polycomb complex facilitates the transition to gene activation during ES cell differentiation. PLoS Genet. 2014 Dec 11;10(12):e1004851. DOI: 10.1371/journal.pgen.1004851.

Vallejo G, La Greca AD, Tarifa-Reischle IC, Mestre-Citrinovitz AC, Ballaré C, Beato M, Saragüeta P. CDC2 mediates progestin initiated endometrial stromal cell proliferation: a PR signaling to gene expression independently of its binding to chromatin. PLoS One. 2014 May 23;9(5):e97311. DOI: 10.1371/journal.pone.0097311.

Millán-Ariño L, Islam AB, Izquierdo-Bouldstridge A, Mayor R, Terme JM, Luque N, Sancho M, López-Bigas N, Jordan A. Mapping of six somatic linker histone H1 variants in human breast cancer cells uncovers specific features of H1.2. Nucleic Acids Res. 2014 Apr;42(7):4474-93. DOI: 10.1093/nar/gku079.

Novellasdemunt L, Obach M, Millán-Ariño L, Manzano A, Ventura F, Rosa JL, Jordan A, Navarro-Sabate A, Bartrons R. Progestins activate 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) in breast cancer cells. Biochem J. 2012 Mar 1;442(2):345-56. DOI: 10.1042/BJ20111418.

Buschbeck M, Uribesalgo I, Wibowo I, Rué P, Martin D, Gutierrez A, Morey L, Guigó R, López-Schier H, Di Croce L. The histone variant macroH2A is an epigenetic regulator of key developmental genes. Nat Struct Mol Biol. 2009 Oct;16(10):1074-9. DOI: 10.1038/nsmb.1665.

Quiles I, Millán-Ariño L, Subtil-Rodríguez A, Miñana B, Spinedi N, Ballaré C, Beato M, Jordan A. Mutational analysis of progesterone receptor functional domains in stable cell lines delineates sets of genes regulated by different mechanisms. Mol Endocrinol. 2009 Jun;23(6):809-26. DOI: 10.1210/me.2008-0454.

Cuscó I, Medrano A, Gener B, Vilardell M, Gallastegui F, Villa O, González E, Rodríguez-Santiago B, Vilella E, Del Campo M, Pérez-Jurado LA. Autism-specific copy number variants further implicate the phosphatidylinositol signaling pathway and the glutamatergic synapse in the etiology of the disorder. Hum Mol Genet. 2009 May 15;18(10):1795-804. DOI: 10.1093/hmg/ddp092.