About

The Innovation in Respiratory Infections and Tuberculosis Group, also known with its acronym One and a Half Group, is located at Germans Trias i Pujol Research Institute (IGTP), Germans Trias i Pujol University Hospital (HUGTiP) and the Genetics and Microbiology Department in the Biosciences Faculty of Universitat Autònoma de Barcelona (UAB). The group is are affiliated with the CIBERES network (CB06/06/0031) and recognised by the Catalan Government as a consolidated research group (2017SGR-0492 and 2021SGR-1267). Thanks to this recognition, the group has cemented its activity and future perspectives. Currently, the team has matured scientifically, developing solid and productive independent research lines. The consolidation of these research lines is a result of their commitment to integrating clinical and translational research into their activities.

The group closely collaborates with the following clinical researchers from HUGTiP: Dr Lourdes Mateo from the Rheumatology Department, Dr Fernando Armestar from the Intensive Care Unit, Dr Irma Casas and Dr Júlia Valera from the Preventive Medicine Department, Dr Maria Méndez and Dr Clara Carreras from the Paediatrics Department, and Dr Zoran Stojanovic, Dr Salome Bellido and Dr Filipe Carvalho from the Pulmonology Department.

Several members of the SGR Group are based outside the Can Ruti Campus: at the Tuberculosis Unit Vall d'Hebron-Drassanes of Hospital Universitari Vall d'Hebron (Dr Maria Luiza de Souza and Dr M. Angeles Jiménez), at Serveis Clínics (Dr Joan Pau Millet and Dr Xavier Casas), at the Pulmonology Department of Hospital Moises Broggi (Dr Fina Sabria), and in the Consorci Sanitari del Maresme (Dr Lydia Luque).

The group is leading European network ADVANCE-TB, a COST Action granted by the European Commission and involving partners from over 50 countries. It also coordinates the recently awarded TB-SPECTRUM project.

Keywords: Diagnostic, host immune response, microbial interaction, environmental factors, antimicrobial therapies.

Group leader

  • José Domínguez Benítez
    José Domínguez Benítez

    José Domínguez Benítez

    Dr José Domínguez studied Biological Sciences at the University of Barcelona, Spain. He completed the Master's Degree in Applied Microbiology and also received a PhD in Microbiology also from the Universidad Autónoma de Barcelona, ​​Spain. He is currently Group Leader at the Germans Trias i Pujol Research Institute (IGTP) in Barcelona, where he leads the research group Innovation in Respiratory Infections and Tuberculosis.

    Dr Domínguez is an associated researcher at the CIBER in Respiratory Diseases (CIBERES). He has been an assistant professor in the Department of Genetics and Microbiology, Faculty of Biosciences at UAB since 2002. He was the coordinator of a European project (INNOVA4TB) working on various aspects of tuberculosis management, involving 16 institutions, including hospitals, research institutes, and Small and medium-sized enterprises (SMEs), with partners from 6 countries. Currently, he is the Scientific Representative for the COST Action (ADVANCE-TB). He has worked in the field of tuberculosis for nearly 30 years, with numerous publications on the body's response to infection, diagnostic methods, and the detection of resistance to major anti-tuberculosis drugs. The group pioneered the study and implementation of immunological and metabolomic techniques for diagnosing TB at both the national and international levels.

    Contact: jadominguez(ELIMINAR)@igtp.cat

    Emerging group leaders

    The research group has two principal investigators who are leading research teams.

    Dr. Irene Latorre studied Biotechnology and has a master in Applied Microbiology. She holds a PhD from the Universitat Autónoma de Barcelona, and is also an assistant professor at the same University. Currently, Irene Latorre is a Miguel Servet researcher leading a research line focused on immune response characterization on respiratory infections.

    Dr. Alicia Lacoma studied Biotechnology and has a master in Applied Microbiology. She holds a PhD from the Universitat Autónoma de Barcelona, and is also an assistant professor at the same University. She is currently leading a research line focused on exploring the impact of air pollutants on respiratory infections using different experimental approaches.

Team

Emerging group leaders
Alicia Lacoma de la Torre(ELIMINAR)
Irene Latorre Rueda(ELIMINAR)

Postdoctoral researchers
Nadiia Tytarenko(ELIMINAR)

PhD students
Salomé Bellido
Iris Romero i Andrada
Guillem Safont Gonzalez
Daria Smalchuk
Zoran Stojanovic(ELIMINAR)
Júlia Valera Paloma(ELIMINAR)

Project manager
Melanie Giorgi(ELIMINAR)

Laboratory technician
Dídac Vulcano Sabadell(ELIMINAR)

Research lines

The group is working in the field of the respiratory infections and tuberculosis, improving the understanding of the host-pathogen-external factors interaction, and exploring new approaches both for diagnosis and treatment.

Scientific challenges and strategic objectives for the next 3 years are described below for each research line.

Microbial interactions

The group’s research explores the microbial mechanisms of adaptation to the respiratory tract and aspects related to clinical presentation together with specific phenotypic and genotypic traits of microorganisms by using novel bioinformatic and genomic approaches. Research is mostly focused on Staphylococcus aureus and Mycobacterium tuberculosis, but Pseudomonas aeruginosa, Streptococcus pneumoniae and Haemophilus influenzae have been also studied for aspects such as carrier status versus colonisation versus infection in the respiratory tract. The objective is to identify differential factors that will allow the design of diagnostic tools to distinguish colonisation from infection, in order to optimise treatment, to design novel targets as well as improve drug delivery systems that will contribute to treatment success and to reduce the emergence of antimicrobial resistance in lower respiratory tract infections.

Immune response characterisation

The group studies the diagnostic and prognostic importance of inflammation markers in different infectious diseases and clinical syndromes, in collaboration with several hospital departments. The team is studying the host immune response to different antigens specific of M. tuberculosis, in both animal models and in humans, and also at peripheral and local level, to characterise the different stages of the TB spectrum. The group has experience in the study of the immune response by conventional and spectral flow cytometry, performing deep immune profiling, as well as studies on the characterisation of different cellular subsets. SARS-CoV-2 immune response has also been characterized in different groups of patients. Finally, the interaction between neutrophils and S.aureus has also been explored, including the formation of NETs after specific stimulation.

Impact of external factors

The group has consolidated the 2D in vitro model of intracellular persistence in murine/human alveolar macrophages, which allows them to carry out trials to explore the impact of environmental pollutants: tobacco smoke, e-vapor of e-cigarette, diesel exhaust particles, and micro and nanoplastics, in the persistence of M.tuberculosis and also S.aureus. They have also studied the impact of pollutants in the immune response against bacteria, and how the bacteria modify its phenotype for adapting to the toxic environment produced by the tobacco.

Diagnostic technology innovation

The team is using molecular, metabolomics and immunological techniques to develop innovative diagnostic technologies. They are also developing and evaluating new molecular methods for studying mutations associated with resistance to anti-TB drugs. In the last years, the group has patented three technologies related with the diagnosis of the mycobacterial infections, and licensed one of them.

New therapeutic approaches

The group is conducting studies involving the search and refinement of anti-infective drugs, but also the use of novel drug delivery systems loaded with conventional S. aureus and M. tuberculosis drugs. Conventional in vitro susceptibility studies are performed; and nanoparticles efficacy are also tested in infection cell models. These nanoparticles are produced by the group led by Dr Manuel Arruebo (Universidad de Zaragoza, Spain). The group is also working on the study of mycobacteriophages as a therapy for mycobacterial infections.

Active projects

TB-SPECTRUM: A step forward for unraveling the immune mechanisms and tools for tuberculosis spectrum management

PI: Irene Latorre
Funding agency: European Comission. HORIZON-MSCA-2024-SE-01
Agency code: 101236673
Duration: 01/01/2026 - 31/12/2029

Multi-centre EuRopean study of MAjor Infectious Disease Syndromes (MERMAIDS) - Acute Respiratory Infections (MERMAIDS ARI) 2.0

Part of the Consortium Rapid European COVID19 Research Response (RECOVER).
Consortium coordinator: Herman Goossens
Sponsor Europe: UMC Utrecht; PI: Patricia Bruijning
Coordinating investigator: C. Prat-Aymerich
PI at HUGTiP: Zoran Stojanovic
Funding agency: European Union's Horizon 2020 research and innovation programme
Agency code: ClinicalTrials.gov identifier NCT04364711, grant agreement No 101003589

Training actions in the field of microbiology, immunology and public health to improve research capabilities in the diagnosis of tuberculosis infection in the child population

PI: Esther Julian (UAB)
Co-PI: José Domínguez
Funding Agency: FUNDACIÓ AUTÒNOMA SOLIDÀRIA. Convocatòria FSXLI
Agency code: FAS41_02
Duration: 01/09/2024 - 31/08/2025

Towards an improvement in diagnostics and treatment strategies for TB control. (ADVANCE-TB)

PI: Alicia Lacoma
Grant Holder Scientific Coordinator: José Domínguez
Grant Awarding Coordinator: Cristina Prat-Aymerich
Funding entity: COST Action. Horizon 2020.
Agency code: CA21164
Duration: 2022 - 2026

Hacia una mejora en las estrategias de diagnóstico y tratamiento y una mejor comprensión del impacto de los factores extrínsecos para el control de la tuberculosis. ADVANCE-TB

PI: J. Domínguez
Funding agency: Instituto de Salud Carlos III (ISCIII)
Agency code: PI22/01834
Duration: 2023 - 2026

A Phase 2, Comparative Randomised Trial to Evaluate the impact of reduced COVID-19 mRNA vaccination regimens on immunological responses and reactogenicity in paediatric subjects with and without prior SARS-CoV-2 infection (CoVacc)

Part of the European Clinical Research Network for the coordination and condult of COVID-19 vaccine trials (VACCELERATE)
Central PI: Patricia Bruijning-Verhagen; Role C.Prat: Lead Medical Monitor
Funding entity: European Union H2020-IBA-SC1-CORONAVIRUS-2020-4
Agency code: Grant agreement number 101037867
Sponsor: UMC Utrecht (Netherlands)

ADEQUATE Advanced Diagnostics for Enhanced QUality of Antibiotic prescription in respiratory Tract infections in Emergency rooms

Consortium VALUE Dx, the value of diagnostics. Coordinator. Herman Goossens
PIs: CPrat, Julia Bielicki. WP4b co-leaders
Funding agency: Innovative Medicines Initiative 2 Joint Undertaking
This Joint Undertaking receives support from the European Union's Horizon 2020 research and innovation programme and EFPIA and bioMérieux SA, Janssen Pharmaceutica NV, Accelerate Diagnostics S.L., Abbott, Bio-Rad Laboratories, BD Switzerland Sàrl, and The Wellcome Trust Limited
Agency code: Grant agreement No 820755.
Sponsor: UMC Utrecht (Netherlands). Currently in process of
sponsorship transfer to Penta Network

Preparedness of the health care system in Ukraine to control TB during and after the war

PI: Andrii Dudnyk
Funding agency: Marie Skłodowska Curie Action for Ukraine (EU-Horizon Europe). Alexander von Humboldt Foundation
Agency code: 1233336
Duration: 2023 - 2025

TB-OMICS: Innovative tuberculosis diagnostic method based on artificial intelligence

PI: Jose Domínguez
Funding Agency: AGAUR. Convocatòria INNOVADORS
Agency code: INNOV-0024
Duration: 01/01/2025 - 30/06/2026

INSPIRE: Impact of air pollutants on respiratory infections and respiratory health

PI: Alícia Lacoma
Funding Agency: Fondo de Investigaciones Sanitarias. Instituto de Salud Carlos III
Agency code: PI24/00032
Duration: 01/01/2025 - 31/12/2027

Past projects

Evaluar la utilidad de una nueva técnica en el diagnóstico de las infecciones por micobacterias no tuberculoses Ref. 18/691

PI: J. Domínguez
Funding agency: Sociedad Española de Neumología y Cirugía Torácica
Duration: 2019 – 2023

BCG vaccination to Reduce the impact of COVID-19 in healthcare workers following Coronavirus Exposure (BRACE) Trial

Chief PI: Nigel Curtis, Murdoch's Children Research Institute Melbourne Australia
PI in Europe: Marc Bonten; Role C.Prat-Aymerich: coordinating investigator (Netherlands and Spain)
PI at HUGTiP: Antoni Rosell Gratacós
Funding agency: Bill and Melinda Gates
Agency code: HREC/protocol no: 62586 NCT04327206. EUDRACT 2020-002503-19
Sponsor in Europe: UMC Utrecht 

Innovation for TB. INNOVA4TB

PI: J. Domínguez
Funding agency: H2020-MSCA-RISE-2018
Agency code: 823854
Duration: 2019 - 2024

Tuberculosis: Development of new diagnostic methods, new host-direct therapies and understanding the impact of extrinsic factors in modulating inflammation (INNOVA2)

PI: J.Domínguez
Funding agency: Instituto de Salud Carlos III (ISCIII)
Agency code: PI19/01408
Duration: 2020 - 2024

ChildTB-Omics: Omics for diagnosis of tuberculosis in children and adolescents

PI: Begoña Santiago
Financing agency: Fondo de Investigaciones Sanitarias - Instituto de Salud Carlos III (ISCIII)
Grant reference: PI20/01607
Duration: 2021 - 2024

Innovative tools to study the impact and mode of action of micro and nanoplastics on human health: towards a knowledge base for risk assessment (PLASTICHEAL)

PI: Ricard Marcos
Financing agency: H2020-SC1-2020-Single-Stage-RTD. Agency code: 965196
Duration: 2021 - 2024

Pneumococcal pNeumonia Epidemiology, Urine serotyping, and Mental Outcomes. The PnEUmo Study in Europe (PNEUMO)

Central PI: M. Bonten; Scientific Coordinator C. Prat Aymerich
PIs at HUGTiP: A. Lacoma and F. Armestar
Funding agency: University Medical Center Utrecht
Agency code: 820755
Duration: 2020 - 2026 (until 2024 in Spain)

Point-of-care tests for the rapid detection of SARS-CoV-2 (POC4CoV)

PI: Maria Pilar Marcos
Financing agency: Fondo COVID-19 - Instituto de Salud Carlos III 8ISCIII)
Agency code: 202050E090
Duration: 2020 - 2021

A multinational, phase 2, randomized, adaptative protocol to evaluate immunogenicity and reactogenicity of different COVID-19 vaccines administration in older adults (>75) already vaccinated against SARS-CoV-2 (EU-COVAT-1_AGED)

Part of the European Clinical Research Network for the coordination and condult of COVID-19 vaccine trials (VACCELERATE)
Coordinator: Prof Oliver A. Cornely
PI at HUGTiP: José Moltó; Laboratory lead: José Domínguez
Funding agency: Horizon 2020
Agency code: Agreement number 101037867. EudraCT nº. 2021-004526-29
Sponsor: University of Cologne (Germany)

Caracterización de la respuesta inmune en el manejo de la infección por SARS-CoV-2

PI: Irene Latorre
Funding agency: Spanish Society of Pulmonology and Thoracic Surgery (SEPAR)
Duration: 2021 - 2024

Deep immune profiling of Mycobacterium tuberculosis local and systemic cell response - TB-IMMUN

PI: Irene Latorre
Financing entity: Instituto de Salud Carlos III (ISCIII)
Agency code: PI21/00724
Duration: 2021 - 2024

Unraveling host systemic and tissue-specific Mycobacterium tuberculosis immunity for a better control of the disease

PI: Irene Latorre
Funding agency: Subdirección General de Evaluación y Fomento de la Investigación
Agency code: CP20/00070
Duration: 2021 - 2024

Facing tuberculosis through urinary biomarkers

PI: J. Domínguez
Funding agency: AGAUR
Agency code: PRODUCTE-0050
Duration: 2023 - 2024

Scientific publications

Highlighted publications

Wheatley RM, Caballero JD, van der Schalk TE, De Winter FHR, Shaw LP, Kapel N, Recanatini C, Timbermont L, Kluytmans J, Esser M, Lacoma A, Prat-Aymerich C, Oliver A, Kumar-Singh S, Malhotra-Kumar S, Craig MacLean R. Gut to lung translocation and antibiotic mediated selection shape the dynamics of Pseudomonas aeruginosa in an ICU patient. Nat Commun. 2022 Nov 22;13(1):6523. DOI: 10.1038/s41467-022-34101-2.

Domínguez J, Boeree MJ, Cambau E, Chesov D, Conradie F, Cox V, Dheda K, Dudnyk A, Farhat MR, Gagneux S, Grobusch MP, Gröschel MI, Guglielmetti L, Kontsevaya I, Lange B, van Leth F, Lienhardt C, Mandalakas AM, Maurer FP, Merker M, Miotto P, Molina-Moya B, Morel F, Niemann S, Veziris N, Whitelaw A, Horsburgh CR Jr, Lange C; TBnet and RESIST-TB networks. Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a 2023 TBnet/RESIST-TB consensus statement. Lancet Infect Dis. 2023 Apr;23(4):e122-e137. DOI: 10.1016/S1473-3099(22)00875-1.

Hamada Y, Gupta RK, Quartagno M, Izzard A, Acuna-Villaorduna C, Altet N, Diel R, Dominguez J, Floyd S, Gupta A, Huerga H, Jones-López EC, Kinikar A, Lange C, van Leth F, Liu Q, Lu W, Lu P, Rueda IL, Martinez L, Mbandi SK, Muñoz L, Padilla ES, Paradkar M, Scriba T, Sester M, Shanaube K, Sharma SK, Sloot R, Sotgiu G, Thiruvengadam K, Vashishtha R, Abubakar I, Rangaka MX. Predictive performance of interferon-gamma release assays and the tuberculin skin test for incident tuberculosis: an individual participant data meta-analysis. EClinicalMedicine. 2023 Jan 5;56:101815. DOI: 10.1016/j.eclinm.2022.101815.

Pittet LF, Messina NL, Orsini F, Moore CL, Abruzzo V, Barry S, Bonnici R, Bonten M, Campbell J, Croda J, Dalcolmo M, Gardiner K, Gell G, Germano S, Gomes-Silva A, Goodall C, Gwee A, Jamieson T, Jardim B, Kollmann TR, Lacerda MVG, Lee KJ, Lucas M, Lynn DJ, Manning L, Marshall HS, McDonald E, Munns CF, Nicholson S, O'Connell A, de Oliveira RD, Perlen S, Perrett KP, Prat-Aymerich C, Richmond PC, Rodriguez-Baño J, Dos Santos G, da Silva PV, Teo JW, Villanueva P, Warris A, Wood NJ, Davidson A, Curtis N; BRACE Trial Consortium Group. Randomized Trial of BCG Vaccine to Protect against Covid-19 in Health Care Workers. N Engl J Med. 2023 Apr 27;388(17):1582-1596. DOI: 10.1056/NEJMoa2212616.

Villar-Hernández R, Latorre I, Noguera-Julian A, Martínez-Planas A, Minguell L, Vallmanya T, Méndez M, Soriano-Arandes A, Baquero-Artigao F, Rodríguez-Molino P, Guillén-Martín S, Toro-Rueda C, De Souza-Galvão ML, Jiménez-Fuentes MÁ, Stojanovic Z, Sabriá J, Santos JR, Puig J, Domínguez-Álvarez M, Millet JP, Altet N, Galea Y, Muriel-Moreno B, García-García E, Bach-Griera M, Prat-Aymerich C, Julián E, Torrelles JB, Rodrigo C, Domínguez J. Development and Evaluation of an NTM-IGRA to Guide Pediatric Lymphadenitis Diagnosis. Pediatr Infect Dis J. 2024 Mar 1;43(3):278-285. DOI: 10.1097/INF.0000000000004211.

ALL PUBLICATIONS

Additional information

Collaborative networks

  • CIBER Respiratory Diseases (CIBERES) Group 17 (CB06/0031), from 2007.
  • Tuberculosis Network European Trials group (TBnet), from 2012.
  • Unidad Asistencial de Excelencia en Tuberculosis, accredited by Sociedad Española de Neumología y Cirugía Torácica (SEPAR), from 2015.
  • Thematic Network in "Systems biology of mycobacteria" (MycoNET). RED2024-153634-T, accredited by Ministerio de Ciencia, Innovación y Universidades, period 2025-2026. 
  • Study Group for Staphylococci and Staphylococcal Diseases. European Society of Clinical Microbiology and Infectious Diseases, from 2018.
  • COMBACTE CLIN-Net. COMBACTE's clinical hospital network was built within COMBACTE-NET, COMBACTE-CARE and COMBACTE-MAGNET, all IMI-funded projects within the New Drugs for Bad Bugs program, dedicated to combat antimicrobial resistance through collaborative research since 2013. In October 2023, COMBACTE will conclude its ten-year mandate: building a sustainable clinical research network. Since 1 June 2022, CLIN-Net was sustained in the European Clinical Research Alliance on Infectious Diseases - ECRAID. That means that the network built over the last decade will continue as part of the not-for-profit ECRAID network.

Doctoral theses

Title: Pooling samples to increase testing capacity for Tuberculosis and COVID-19 diagnosis
Author: Vibol Iem (Laos)
Supervisors: International PhD Supervision
Primary supervisors: Tom Wingfield, Luis E. Cuevas
Secondary supervisors: Jose Dominguez, Jahangir Khan
Institution: Liverpool School of Tropical Medicine (UK)
Academic year of defence: 2022-2023

Title: Study of pulmonary and systemic markers for the characterization of the immune response against Mycobacterium tuberculosis in mice and human
Author: Sergio Díaz Fernández
Supervisors: J. Domíngez, I. Latorre
University: Universitat Autònoma de Barcelona
Academic year of defence: 2023-2024

Title: Assessing the incidence of COVID-19 infection among the frontline healthcare workers in the federal capital territory, Abuja, Nigeria
Author: Saddiq T. Abdurrhaman (Nigeria)
Supervisor: J. Domínguez
University: Universitat Autònoma de Barcelona (UAB)
Academic year of defence: 2022-2023

Innovation 

The team exhibits a pro-active tech transfer behaviour. The group holds three patents in national phases. Two of them are licensed, and the third is in negotiations with an IVD Company. In all cases, the group has been invited to participate in the co-development of the final product. In one case, a member of the group was employed for a full year in the R+D department of the company, and will now be hired to be in charge of the final steps of the market release.

In vitro method for the diagnosis or detection of non-tuberculous mycobacteria
Inventors: J. Domínguez, J. Torrelles, I. Latorre i R. Villar-Hernández
Entity: Institut d'Investigació Germans Trias i Pujol; CIBERES; The Ohio State University
Reference: PCT/EP2019/066055. WO 2019/234296 A1
Date: 12/12/2019
Status: Licenced in 16 September 2020

Identification of metabolomic signatures in urine samples for tuberculosis diagnosis
Inventors: J. Domínguez, JL Izquierdo, P Comella i C. Prat
Entity: Institut d'Investigació Germans Trias i Pujol; CIBER
Reference: PCT/EP2019/064885. WO 2019/243347 A1
Date: 26/12/2019

In vitro method for discriminating latent from active tuberculosis
Inventors: J. Domínguez, T. Pérez-Porcuna, P. Comella, i R. Abellana
Entity: Fundació Mútua de Terrassa, Institut d'Investigació Germans Trias i Pujol, Universitat de Barcelona
Reference: PCT/EP2020/070810. WO 2021/013933 A1
Date: 23/07/2019

Outreach 

The group is establishing participatory multi-actor dialogues between researchers, policy makers, industry, and civil society organisations, NGOs, and citizens to define the scientific research priorities.

In 2021, the group organised, with the collaboration of TB-REP 2.0, a symposium for discussing the role of civil society in TB diagnostics and management. TB-REP 2.0 is a multi-country program covering 11 countries in the Eastern Europe region. Representatives of more than 25 small and medium NGOs from Eastern Europe and Euro-Asia countries participated in the event. During the symposium, the need for non-invasive methods that provide rapid results was emphasised as key to reducing the burden of the disease, reducing the stigma that patients suffer, and increasing the well-being of the citizens and the society.

The group also participated, in 2021, in an international online course about "Community Engagement in TB Research & Development: Looking for Innovations", oriented to civil society that was also organized in collaboration with TB-REP 2.0. The group discussed with representatives of the civil society about the preventive therapy of tuberculosis, and the needs of diagnostics and vaccines. These actions contribute to building a more scientifically literate society able to actively participate in and support democratic processes, and science and technology developments.

They organised a symposium in December 2024, entitled "Engaging community in TB research and development: conducting TB community based and led research to inform TB policy". In this case organised by ADVANCE-TB (COST-Action), and the project "EECA post UNHLM community watch to leave no one behind" granted by STOP-TB-Partnership. More than 25 NGOs participated bringing together key TB community and CSOs to learn about research and trials, methods of data collection; learning what steps on data is required to conduct meaningful community lead and/or basic research; and how scale up the results of the research to communities through policy translation, including diagnostic algorithms.

The group plans to continue in contact with the NGOs for involving them in the research strategies of the group.

Continuous information will be released from the group through social networks (X, LinkedIn, Instagram, and Facebook; @Oneandahalf_Lab; @innova4tb), and conventional media (Newspaper, radio, and TV).

News

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- Success Stories, Outreach

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