About
With increasing healthcare costs and decreasing numbers of healthcare professionals, the application of technology to healthcare has become essential. Technological developments are increasing at a rapid rate and digital innovations are steadily making their way into everyday clinical practice. This means that the skills that new professionals are required to maser are rapidly transforming not just the healthcare curriculum, but also the way healthcare institutions function and care pathways they provide. In addition, assessing the feasibility, viability and cost-effectiveness of new approaches is often a challenging and daunting process, which needs to be approached in a scholarly fashion.
The Innovation, Health Economics and Digital Transformation Research Group (INEDIT) at the Germans Trias i Pujol Research Institute was set up in early 2022; it brings together specialists in a number of different areas. The overarching aim of the group is to conduct applied transversal research with the vision of impacting the healthcare model, it will do this by connecting multidisciplinary teams, consisting of management, innovation, digital transformation, knowledge transfer and health economics experts.
Keywords: Innovation, health economics, digital health, digital transformation, processes, healthcare, research.
Group leader
- Oriol Estrada Cuxart, PhD, MD
Oriol Estrada Cuxart, PhD, MD
Oriol Estrada Cuxart, a University of Barcelona medicine graduate (1987) and internal medicine specialist, boasts a distinguished career enriched by a PhD in Clinical Innovation from Universitat Autònoma de Barcelona, focusing on home endovenous treatments for serious infections. Further honing his expertise, he earned a diploma in Integrated Health Services Management from ESADE Business School in 2011. Estrada has since ascended to prominent leadership roles in healthcare, notably spearheading health strategy and innovation in Catalonia's North Metropolitan Area, impacting over 1.5 million residents through his leadership in over 100 integration and innovation projects.
Estrada's expertise centers on clinical innovation, driving significant improvements in care and health outcomes. He initiated a pioneering technological innovation program addressing healthcare professionals' needs directly from the front lines. As a prolific contributor to his field, Estrada has authored numerous publications and presented at both national and international forums across various domains, including innovation, hospital management, and clinical management.
He played a pivotal role in founding the INEDIT Research Group at IGTP, serving as the group leader and coordinating the Evaluation and health economics research line. Currently, Estrada directs the master's degree program in eHealth at La Salle Barcelona-Universitat Ramon Llull, further cementing his legacy as a leader in healthcare innovation and education.
Contact: oestrada(ELIMINAR)@gencat.cat
ORCID: 0000-0003-1414-5000
Team
Principal investigators
Meritxell Davins Riu, PhD, MD(ELIMINAR) – Digital transformation line. Group Coordinator
Josep Maria Ibañez Romaguera, PhD, MD(ELIMINAR) – Assistance transformation line: alliances and cross-cutting processes
Daniel Moreno Martinez, PhD, FHEA(ELIMINAR) – Innovation line
Raül Zurita Badosa, PhD(ELIMINAR) – Early-stage evaluation of new health technologies (early HTA)
Associate researchers
Mercè Bonjorn Dalmau, PhD(ELIMINAR)
Guillem Hernandez Guillament(ELIMINAR)
Mireia Cano Izquierdo(ELIMINAR)
Maria Isabel Martinez Segura(ELIMINAR)
Laura Miró Mezquita(ELIMINAR)
Gerard Albreda Gil(ELIMINAR)
Eloi Querol Carranza(ELIMINAR)
Raquel Escrich Navarro, PhD(ELIMINAR)
Pablo Alegre Cabrera
Patricia Valero Valdelvira
Marta Alemany Carro
Juan Carrillo Reixach
Josep Maria Torras Otaola
Jordi Taboada Bernal
Estela Palahí Navarro
Marc Danés Castells
Jose Ángel Vicente Gómez
Maria Teresa Prats Villar
Andrea Requena
Research lines
Evaluation and health economics
This line of research is based on two axes:
- Economic evaluation studies. With the aim of providing strategic campus projects and other innovation and research initiatives with an approach focused on health outcomes and the positive impact/return generated by the intervention under study. Various economic evaluation strategies are applied:
- Cost/benefit analysis
- Cost/effectiveness analysis
- Cost/utility analysis
- Cost minimisation analysis
- Multidimensional evaluation of value-based health innovation projects. The group develops and validates its own methodology to evaluate the entire innovation/care transformation cycle of projects carried out in the territory. The aim is to develop and validate open-source support and evaluation instruments that facilitate the dissemination of the value-based outcome assessment culture.
Assistance transformation line: alliances and cross-cutting processes
Within the healthcare transformation strategy, and complementary to other areas such as digital transformation and health and innovation, the key objective is organisational innovation based on new forms of integrated, cooperative and networked work with other institutions or levels of care. These are projects aimed at responding to an undeniable reality of the health system, given the risk of leaving care services uncovered or insufficiently covered, which generates numerous dysfunctions in the system that lead, all in all, to a growing dissatisfaction both among citizens and among professionals.
This transformation process can be synthesized into:
- Creation of territorial services through strategic alliances with planning and sustainability criteria, in order to maintain equity of access to health services, greater excellence in care, adequate levels of quality and improvement in the satisfaction of professionals and citizens. A secondary objective of this network is to establish an efficient, equitable, and sustainable care model, alongside the evaluation of its cost-benefit outcomes.
- Integration of health processes from the perspective of value-based medicine such as:
- The integrated model of attention to complex chronicity (ProPCC)
- The biopsychosocial approach to the management of neglected diseases such as tuberculosis or schistosomiasis
- The creation of integrated multidisciplinary units with AP and oriented to the care process
- Redesign of specific care processes.
Technological innovation
This line focuses on the study, design and evaluation of strategies and tools to promote technological innovation in healthcare environments. The main lines of work are:
- Health innovation management: development of models and tools to structure and optimize the management of innovation projects in health centers.
- Adoption and implementation of innovation: analysis of barriers and facilitators in the incorporation of new technologies and processes, as well as design of strategies for their effective implementation and scalability.
- Implementation and evaluation of innovative solutions: study and piloting of innovative tools, services and solutions in the field of health, including the analysis of their usefulness, acceptability, feasibility and clinical and organizational impact.
- Culture of innovation: research aimed at understanding the functioning of the different innovation cultures existing in the health context.
- Trends in innovation in health: monitoring and prospective analysis of emerging trends in technology, care models and health organization to guide the innovation strategy of the system.
Early-stage evaluation of new health technologies (early HTA)
This line of research focuses on the analysis of the potential value of new health technologies in early stages of development. The objective is to facilitate informed decision-making in the early stages of innovation, in order to guide the design, development and marketing strategy of these solutions. The areas of work include:
- Preliminary valorisation of emerging technologies: application of adapted HTA tools to assess the clinical relevance, potential impact and economic viability of new solutions before their implementation.
- Evaluation of uncertainty and expected impact: identification of evidence gaps and risk analysis associated with the introduction of new technologies.
- Collaboration with innovation ecosystem stakeholders: support for spin-offs, start-ups, and research projects in defining their value proposition and evidence generation strategy.
- Integration of early HTA into healthcare innovation processes: promotion of value-based and evidence-based decision models, from the initial stages of technological development.
Digital transformation and health
The Digital transformation line enhances existing research by providing technologies that facilitate data collection and, at the same time, it opens up new lines of investigation aimed at measuring how digitalisation impacts health indicators and user experience. The overarching mission is value-based healthcare. The active lines of research are:
- Results, efficiency and impact on health: measuring the impact of the implementation of Telemedicine and other technological tools in different services together with a reengineering of processes.
- Accessibility and health literacy: measuring the digital divide and the level of health literacy in patients, the impact that actions have to improve health literacy, and identifying digital determinants.
- User experience: evaluation of digital interventions such as eSalut to measure the quality and effectiveness of health care from the perspective of patients.
- Biases: analysis of the accuracy of the data provided by patients and study of solutions to minimize them.
- Adherence: technological solutions such as eSalut allow us to monitor more exhaustively adherence to treatments.
Active projects
- MoniK project (Monitorización Hiperpotasemia en Paciente Crónico Renal bajo Diálisis) – Code: CPP2022-009868
- ASSIST project (Artificial Intelligence Scalable Solution for ST Myocardial Infarction) – Code: 230193
- CRIPAP project: Hearing loss screening of a population area
- EIT Health - iDays
- IHI CAREPATH
- EIT Health - adoptHIT/HIAPST – Code: 2024-CERT-8646
- EIT Health - PIPRA SAGE – Code: 2024-ITM-8924
- PCP Carematrix
- PCP Rosia
- Auspire
- Projecte Transformador del CatSalut SESHAT (telemonitoratge, automatizació del procés del medicament, imatge digital quirúrgica) – Code: PT-012023-EP SESHAT
Past projects
- CRIPAP project: Hearing loss screening of a population area – Code: CPP 2021-008549
- EIT Health - Healthcare Transformation Academy – Code: 210615 / 230133
- Erasmus+ - 4D – Code: 2021-1-ES01-KA220-HED-000027496
- Erasmus+ - HEAL – Code: 2021-1DK01-KA220-HED-000032211
- Cost-effectiveness study of the CardioMEMS device
- Cost-effectiveness study of the ProPCC program
- Cost-benefit analysis of the implementation of a vascular access team
- Economic impact of the implementation of a multidisciplinary diabetic foot clinic
- Economic impact in local economy of Germans Trias Research Institute activity
- Implementation of the International Lung Screening Trial in Catalonia (Spain): An Economic Analysis. - PREprint
- Dry Wipes for Hygiene in Hospitalized Patients: Economic and Environmental Impact, and Patient and Professional Satisfaction
Scientific publications
Highlighted publications
López Seguí F, Estrada Cuxart O, Mitjà I Villar O, Hernández Guillamet G, Prat Gil N, Maria Bonet J, Isnard Blanchar M, Moreno Millan N, Blanco I, Vilar Capella M, Català Sabaté M, Aran Solé A, Argimon Pallàs JM, Clotet B, Ara Del Rey J. A Cost-Benefit Analysis of the COVID-19 Asymptomatic Mass Testing Strategy in the North Metropolitan Area of Barcelona. Int J Environ Res Public Health. 2021 Jun 30;18(13):7028. DOI: 10.3390/ijerph18137028.
López Seguí F, Oyón Lerga U, Laguna Marmol L, Coll P, Andreu A, Meulbroek M, Lopez Casasnovas G, Estrada Cuxart O, Ara Rey J, Quiñones C, Perez F, Fernandez J, Rivero A, Ricou Rios L, Clotet B. Cost-effectiveness analysis of the daily HIV pre-exposure prophylaxis in men who have sex with men in Barcelona. PLoS ONE. 2023 Jan 17;18(1):e0277571. DOI: 10.1371/journal.pone.0277571.
López Seguí, F.; Navarrete Duran, J.M.; Tuldrà, A.; Sarquella, M.; Revollo, B.; Llibre, J.M.; Ara del Rey, J.; Estrada Cuxart, O.; Paredes Deirós, R.; Hernández Guillamet, G.; Clotet Sala, B.; Vidal Alaball, J.; Such Faro, P. Impact of Mass Workplace COVID-19 Rapid Testing on Health and Healthcare Resource Savings. Int. J. Environ. Res. Public Health. 2021 Jul 3;18(13):7129. DOI: 10.3390/ijerph18137129.
López, F.; Català, M.; Prats, C.; Estrada, O.; Oliva, I.; Prat, N.; Isnard, M.; Vallès, R.; Vilar, M.; Clotet, B.; Argimon, J.M.; Aran, A.; Ara, J. A Cost-Benefit Analysis of COVID-19 Vaccination in Catalonia. Vaccines (Basel). 2021 Dec 31;10(1):59. DOI: 10.3390/vaccines10010059.
Davins Riu M, Borràs Pérez X, Artigas Raventós V, Palomera Fanegas E, Serra Prat M, Alós Villacrosa J. Use of Telehealth as a New Model for Following Intermittent Claudication and Promoting Patient Expertise. Telemed J E Health. 2018 Oct;24(10):773-781. DOI: 10.1089/tmj.2017.0226.
Porras JG, Grau I, Davins M, Arenós R, Parra L, De Lourdes MI. ¿Qué hemos aprendido del COVID-19? ReMUE.c@t. 2020;7(1)13-13. Extracted from: https://www.remue.cat/view_document.php?tpd=2&i=16199
Torres M, Reixach E, Magem D, Gimenez E, Andrés E, Moreno-Martinez D, Espallargues M, en nom del grup de treball interinstitucional en innovació tecnològica per a la crisi de la COVID-19. PriTec-COVID-19: una eina per a la priorització de la innovació. Barcelona: Agència de Qualitat i Avaluació Sanitàries de Catalunya. Departament de Salut. Generalitat de Catalunya; 2021.
Gimenez E, Torres M, Moreno-Martinez D, Reixach E, Magem D, et al. (in press, 2022). Unmet needs for COVID-19 non-pharmacological innovative technology in Catalonia. Lessons learned for improvement of quality healthcare. IJQHC Communications.
Guillamet GH, Seguí FL, Vidal-Alaball J, López B. CauRuler: Causal irredundant association rule miner for complex patient trajectory modelling. Comput Biol Med. 2023 Feb 9;155:106636. DOI: 10.1016/j.compbiomed.2023.106636.
Roure S, López F, Oliva I, Pérez-Quílez O, March O, Chamorro A, Abad E, Muñoz IL, Castillo A, Soldevila L, Valerio L, Lozano M, Masnou H, Oliveira M, Cañas L, Gibrat M, Chuecos M, Montero JJ, Colmenares K, Falguera G, Bonet JM, Isnard M, Prat N, Estrada O, Clotet B, Vallès X. Schistosomiasis screening in non-endemic countries from a cost perspective: Knowledge gaps and research priorities. The case of African long-term residents in a Metropolitan Area, Spain. PLoS Negl Trop Dis. 2023 Apr 4;17(4):e0011221. DOI: 10.1371/journal.pntd.0011221.
Mas MÀ, Miralles R, Ulldemolins MJ, Garcia R, Gràcia S, Picaza JM, Navarro Fernández M, Rocabayera MA, Rivera M, Relaño N, Torres Asensio M, Laporta P, Morcillo C, Nadal L, Hervás R, Fuguet D, Alba C, Miralles Banqué N, Jiménez Panés S, Moreno Moreno M, Nogueras C, Manjón Navarro H, López R, Hernández G, López-Seguí F, Ríos LR, Pons A, Prat N, Ara Del Rey J, Estrada O. Evaluating Person-Centred Integrated Care to People with Complex Chronic Conditions: Early Implementation Results of the ProPCC Programme. International Journal of Integrated Care, 2023; 23(4): 18, 1-12. DOI: https://doi.org/10.5334/ijic.7585.
Additional information
Collaborative networks
XaRFA - Reference Network in Additive Manufacturing of Catalonia
Mission: Improve the transfer, valorization and internationalization of research around additive manufacturing developed by the Catalan R+D+I network.
Vision: With an eye on this milestone, the XaRFA Valorization and Transfer Program aims to become the link between the market and the Catalan research fabric in the field of 3D printing technology, positioning itself as the European benchmark in additive manufacturing and its applications.
Values: The actions of the XaRFA are based on the commitment to the institutions and member entities, the responsibility to generate shared and enriching synergies, and the generation of value to society with quality technological solutions.
Member entities: The XaRFA, led by CIM UPC (the UPC technology center leader in advanced production technologies), is made up of a total of 28 research groups from 14 institutions across Catalonia, including IGTP.
More information on the network can be found in the XaRFA website.
News
IGTP involved in three European innovation projects receiving over 12 million euros in funding
The IGTP, through the INEDIT group, is involved in three major European projects committed to health innovation, with over €12 million in funding.
Screening high-risk groups for tuberculosis in low-incidence countries: a cost-effective strategy
A study led by researchers from IGTP, in collaboration with health economics experts from Can Ruti, UPF, and Agència de Salut Pública de Barcelona, offers new recommendations for optimising tuberculosis screening programmes in low-incidence countries. Published in the journal Eurosurveillance, this work reviews various studies to determine if these programmes targeting higher-risk groups are economically effective.